Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Napepldtm1.2Ueda
Name:	N-acyl phosphatidylethanolamine phospholipase D; targeted mutation 1.2, Natsuo Ueda
MGI ID:	MGI:5296775
Synonyms:	NAPE-PLD-, Napepldtm1.2Itl
Gene:	Napepld  Location: Chr5:21867899-21906394 bp, - strand  Genetic Position: Chr5, 9.97 cM
Alliance:	Napepldtm1.2Ueda page

Germline Transmission:	Earliest citation of germline transmission: J:177598
Parent Cell Line:	iTL1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed exon 3. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:177598)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Napepld Mutation:	24 strains or lines available

Original:	J:177598 Tsuboi K, et al., Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. Biochim Biophys Acta. 2011 Oct;1811(10):565-77
All:	2 reference(s)