Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mcm10tm1Hlee
Name:	minichromosome maintenance 10 replication initiation factor; targeted mutation 1, Ho Lee
MGI ID:	MGI:5296322
Gene:	Mcm10  Location: Chr2:4995535-5017602 bp, - strand  Genetic Position: Chr2, 3.12 cM, cytoband A1
Alliance:	Mcm10tm1Hlee page

Germline Transmission:	Earliest citation of germline transmission: J:177618
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     Exons 4 through 6 were replaced with a puro cassette. (J:177618)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mcm10 Mutation:	55 strains or lines available

Original:	J:177618 Lim HJ, et al., Targeted disruption of Mcm10 causes defective embryonic cell proliferation and early embryo lethality. Biochim Biophys Acta. 2011 Oct;1813(10):1777-83
All:	1 reference(s)