Hsp90aa1tm1.1Udon
Targeted Allele Detail
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Symbol: |
Hsp90aa1tm1.1Udon |
Name: |
heat shock protein 90, alpha (cytosolic), class A member 1; targeted mutation 1.1, Heiichiro Udono |
MGI ID: |
MGI:5294812 |
Gene: |
Hsp90aa1 Location: Chr12:110657470-110662829 bp, - strand Genetic Position: Chr12, 60.75 cM
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Alliance: |
Hsp90aa1tm1.1Udon page
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Germline Transmission: |
Earliest citation of germline transmission:
J:177143
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A floxed neo cassette was inserted upstream of exon 9. An additional loxP site was inserted downstream of exon 10. Cre-mediated recombination removed the neo cassette and exons 9 and 10. The absence of protein expression was confirmed by western blot analysis on liver, kidney, lung, brain, tesis, and bone marrow-derived dendritic cells.
(J:177143)
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Generation of the Hsp90aa1tm1.1Udon allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Hsp90aa1 Mutation: |
38 strains or lines available
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Original: |
J:177143 Imai T, et al., Heat shock protein 90 (HSP90) contributes to cytosolic translocation of extracellular antigen for cross-presentation by dendritic cells. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16363-8 |
All: |
4 reference(s) |
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