Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Csn1s1tm1Afk
Name:	casein alpha s1; targeted mutation 1, Andreas F Kolb
MGI ID:	MGI:5285947
Gene:	Csn1s1  Location: Chr5:87814067-87830437 bp, + strand  Genetic Position: Chr5, 43.56 cM
Alliance:	Csn1s1tm1Afk page

Germline Transmission:	Earliest citation of germline transmission: J:174932
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A a pgk promoter driven hygromycin-thymidine kinase fusion gene replaced exon 2 and some of the surrounding genomic region via homologous recombination. (J:174932)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csn1s1 Mutation:	29 strains or lines available

Original:	J:174932 Kolb AF, et al., Milk lacking alpha-casein leads to permanent reduction in body size in mice. PLoS One. 2011;6(7):e21775
All:	1 reference(s)