Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dnm3tm1.2Pdc
Name:	dynamin 3; targeted mutation 1.2, Pietro De Camilli
MGI ID:	MGI:5285526
Gene:	Dnm3  Location: Chr1:161810022-162305603 bp, - strand  Genetic Position: Chr1, 69.95 cM
Alliance:	Dnm3tm1.2Pdc page

Germline Transmission:	Earliest citation of germline transmission: J:175247
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S1/Sv and C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination removed exon 2 and the neo cassette. The absence of protein expression was confirmed by western blot analysis on brain, testis, and lung extracts. (J:175247)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dnm3 Mutation:	63 strains or lines available

Original:	J:175247 Raimondi A, et al., Overlapping role of dynamin isoforms in synaptic vesicle endocytosis. Neuron. 2011 Jun 23;70(6):1100-14
All:	6 reference(s)