Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Khsrptm1.1Cyc
Name:	KH-type splicing regulatory protein; targeted mutation 1.1, Ching-Yi Chen
MGI ID:	MGI:5285092
Gene:	Khsrp  Location: Chr17:57328049-57338507 bp, - strand  Genetic Position: Chr17, 29.63 cM
Alliance:	Khsrptm1.1Cyc page

Germline Transmission:	Earliest citation of germline transmission: J:175084
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1 through 13 were replaced with a floxed hygro cassette. Cre-mediated recombination removed the hygro cassette. Northern blot analysis confirmed the absence of transcript expression. (J:175084)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Khsrp Mutation:	33 strains or lines available

Original:	J:175084 Lin WJ, et al., Posttranscriptional Control of Type I Interferon Genes by KSRP in the Innate Immune Response against Viral Infection. Mol Cell Biol. 2011 Aug;31(16):3196-207
All:	10 reference(s)