Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lcn2tm1Mrgr
Name:	lipocalin 2; targeted mutation 1, Michael R Green
MGI ID:	MGI:5052158
Synonyms:	24p3-
Gene:	Lcn2  Location: Chr2:32274649-32277751 bp, - strand  Genetic Position: Chr2, 22.09 cM, cytoband A3
Alliance:	Lcn2tm1Mrgr page

Germline Transmission:	Earliest citation of germline transmission: J:173490
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1 through 5 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on urine samples. (J:173490)

Generation of the Lcn2tm1Mrgr/Lcn2tm1Mrgr null mice

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lcn2 Mutation:	27 strains or lines available

Original:	J:173490 Liu Z, et al., Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3. J Biol Chem. 2011 Jun 10;286(23):20606-14
All:	3 reference(s)