Summary | Mutation origin | Mutation description | Find Mice (IMSR) | Notes | References

Symbol:	Mitftm3Arnh
Name:	melanogenesis associated transcription factor; targeted mutation 3, Heinz Arnheiter
MGI ID:	MGI:5050698
Gene:	Mitf  Location: Chr6:97784013-97998310 bp, + strand  Genetic Position: Chr6, 45.05 cM
Alliance:	Mitftm3Arnh page

Germline Transmission:	Earliest citation of germline transmission: J:188155
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	(C57BL/6N x 129S6/SvEvTac)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The targeted mutation deleted the D promoter, exon 2D and the flanking intron by the addition of a floxed neomycin selection cassette. (J:188155)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mitf Mutation:	72 strains or lines available

Original:	J:188155 Bharti K, et al., A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757
All:	1 reference(s)