Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Tmem234tm1Lex
Name:	transmembrane protein 234; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID:	MGI:5006992
Gene:	Tmem234  Location: Chr4:129494449-129502326 bp, + strand  Genetic Position: Chr4, 63.26 cM, cytoband D2.3
Alliance:	Tmem234tm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:171883
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A portion of the coding region was targeted by homologous recombination. The gene consists of 5 exons, with the start codon located in exon 1 (NCBI accession NM_029748.1). Exons 4 and 5 were targeted. Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tmem234 Mutation:	37 strains or lines available

Original:	J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:	2 reference(s)