Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Ppargc1atm1.1Amos
Name:	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha; targeted mutation 1.1, Antonio Moschetta
MGI ID:	MGI:4950745
Synonyms:	PGC1a-, PGC1alpha-
Gene:	Ppargc1a  Location: Chr5:51611592-51725068 bp, - strand  Genetic Position: Chr5, 27.02 cM, cytoband C1
Alliance:	Ppargc1atm1.1Amos page

Germline Transmission:	Earliest citation of germline transmission: J:171361
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	C57BL/6JOlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neomycin selection cassette replaced sequence spanning from intron 2 through intron5 (deleting exons 3-5). The selection cassette was subsequently excised by breeding to a cre-deleter mouse strain. (J:171361)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppargc1a Mutation:	47 strains or lines available

Original:	J:171361 D'Errico I, et al., Peroxisome proliferator-activated receptor-{gamma} coactivator 1-{alpha} (PGC1{alpha}) is a metabolic regulator of intestinal epithelial cell fate. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6603-8
All:	2 reference(s)