Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kcnu1tm1.2Clin
Name:	potassium channel, subfamily U, member 1; targeted mutation 1.2, Christopher J Lingle
MGI ID:	MGI:4949763
Gene:	Kcnu1  Location: Chr8:26339651-26427967 bp, + strand  Genetic Position: Chr8, 14.17 cM, cytoband A3
Alliance:	Kcnu1tm1.2Clin page

Germline Transmission:	Earliest citation of germline transmission: J:171225
Parent Cell Line:	B6/BLU (ES Cell)
Strain of Origin:	C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination removed exon 27, the EGFP, and the neo cassette. The absence of protein expression was confirmed by western blot analysis on testes extracts. (J:171225)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnu1 Mutation:	63 strains or lines available

Original:	J:171225 Zeng XH, et al., Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoa. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5879-84
All:	4 reference(s)