Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Map1stm1.1Lliu
Name:	microtubule-associated protein 1S; targeted mutation 1.1, Leyuan Liu
MGI ID:	MGI:4948361
Gene:	Map1s  Location: Chr8:71358618-71370173 bp, + strand  Genetic Position: Chr8, 34.41 cM
Alliance:	Map1stm1.1Lliu page

Germline Transmission:	Earliest citation of germline transmission: J:170757
Parent Cell Line:	AK7 (ES Cell)
Strain of Origin:	129S4/SvJaeSor

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination removed exons 4 and 5. The absence of protein expression was confirmed by western blot analysis on heart extracts. (J:170757)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Map1s Mutation:	35 strains or lines available

Original:	J:170757 Xie R, et al., Microtubule-associated Protein 1S (MAP1S) Bridges Autophagic Components with Microtubules and Mitochondria to Affect Autophagosomal Biogenesis and Degradation. J Biol Chem. 2011 Mar 25;286(12):10367-77
All:	6 reference(s)