Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dusp4tm1Plev
Name:	dual specificity phosphatase 4; targeted mutation 1, Robin Plevin
MGI ID:	MGI:4947517
Gene:	Dusp4  Location: Chr8:35274451-35287048 bp, + strand  Genetic Position: Chr8, 21.16 cM
Alliance:	Dusp4tm1Plev page

Germline Transmission:	Earliest citation of germline transmission: J:170774
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neo cassette replaced exons 2, 3, and 4. The absence of protein expression was confirmed by western blot analysis on bone marrow-derived macrophages stimulated with LPS. (J:170774)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dusp4 Mutation:	22 strains or lines available

Original:	J:170774 Al-Mutairi MS, et al., MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana. PLoS Pathog. 2010;6(11):e1001192
All:	11 reference(s)