Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ecm1tm1Bsun
Name:	extracellular matrix protein 1; targeted mutation 1, Bing Sun
MGI ID:	MGI:4940879
Gene:	Ecm1  Location: Chr3:95641459-95646880 bp, - strand  Genetic Position: Chr3, 40.91 cM
Alliance:	Ecm1tm1Bsun page

Germline Transmission:	Earliest citation of germline transmission: J:168252
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2 through 11 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on CD4+ T cell subsets. (J:168252)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ecm1 Mutation:	34 strains or lines available

Original:	J:168252 Li Z, et al., ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1). Nat Immunol. 2011 Feb;12(2):178-85
All:	3 reference(s)