Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pycr1tm1(KOMP)Vlcg
Name:	pyrroline-5-carboxylate reductase 1; targeted mutation 1, Velocigene
MGI ID:	MGI:4881190
Synonyms:	Pycr1-
Gene:	Pycr1  Location: Chr11:120527591-120534602 bp, - strand  Genetic Position: Chr11, 84.37 cM
Alliance:	Pycr1tm1(KOMP)Vlcg page
IMPC:	Pycr1 gene page

Mutant Cell Lines:	14897A-D8, 14897A-D11, 14897A-E9, 14897A-F12, 14897A-G3, 14897A-H3
Germline Transmission:	Earliest citation of germline transmission: J:188991
Parent Cell Line:	VGB6 (ES Cell)
Strain of Origin:	C57BL/6NTac
Project Collection:	KOMP-Regeneron

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1   Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3250bp between positions 120530799-120534048 of Chromosome 11 (Build GRCm39). (J:136110)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Pycr1 Mutation:	21 strains or lines available

Original:	J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:	3 reference(s)