Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Klrd1tm1.1Lll
Name:	killer cell lectin-like receptor, subfamily D, member 1; targeted mutation 1.1, Lewis L Lanier
MGI ID:	MGI:4880661
Gene:	Klrd1  Location: Chr6:129568745-129575738 bp, + strand  Genetic Position: Chr6, 63.42 cM
Alliance:	Klrd1tm1.1Lll page

Germline Transmission:	Earliest citation of germline transmission: J:167730
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neo cassette replaced part of exon 3 and all of exon 4. Cre-mediated recombination removed the neo cassette. The absence of the receptor heterodimers as confirmed by splenocyte labelling and sorting. (J:167730)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Klrd1 Mutation:	17 strains or lines available

Original:	J:167730 Orr MT, et al., Development and function of CD94-deficient natural killer cells. PLoS One. 2010;5(12):e15184
All:	3 reference(s)