Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pax5tm3.1Mbu
Name:	paired box 5; targeted mutation 3.1, Meinrad Busslinger
MGI ID:	MGI:4879988
Synonyms:	Pax5delta, Pax5tm2Mbu
Gene:	Pax5  Location: Chr4:44524757-44710487 bp, - strand  Genetic Position: Chr4, 23.55 cM
Alliance:	Pax5tm3.1Mbu page

Germline Transmission:	Earliest citation of germline transmission: J:75504
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exon 2, which encodes the amino-terminal portion of the paired domain essential for DNA binding, was deleted after in vivo recombination of the Pax5tm3Mbu allele. (J:75504)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pax5 Mutation:	35 strains or lines available

Original:	J:75504 Horcher M, et al., Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis. Immunity. 2001 Jun;14(6):779-90
All:	3 reference(s)