Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ahnaktm1Ysb
Name:	AHNAK nucleoprotein; targeted mutation 1, Yun Soo Bae
MGI ID:	MGI:4868713
Gene:	Ahnak  Location: Chr19:8966648-9054278 bp, + strand  Genetic Position: Chr19, 6.04 cM, cytoband A
Alliance:	Ahnaktm1Ysb page

Germline Transmission:	Earliest citation of germline transmission: J:167668
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: 502 bp of the promoter and translational start codon were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts. (J:167668)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ahnak Mutation:	316 strains or lines available

Original:	J:167668 Lee IH, et al., Ahnak protein activates protein kinase C (PKC) through dissociation of the PKC-protein phosphatase 2A complex. J Biol Chem. 2008 Mar 7;283(10):6312-20
All:	7 reference(s)