Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Csgalnact1tm1.1Migar
Name:	chondroitin sulfate N-acetylgalactosaminyltransferase 1; targeted mutation 1.1, Michihiro Igarashi
MGI ID:	MGI:4868209
Synonyms:	T1KO
Gene:	Csgalnact1  Location: Chr8:68809433-69187798 bp, - strand  Genetic Position: Chr8, 33.88 cM
Alliance:	Csgalnact1tm1.1Migar page

Germline Transmission:	Earliest citation of germline transmission: J:166870
Parent Cell Line:	RENKA (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 7, and an additional loxP site was inserted downstream of exon 7. Cre-mediated recombination removed exon 7 and the neo cassette. The absence of protein expression was confirmed by western blot analysis on E18.5 head extracts. (J:166870)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	23 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csgalnact1 Mutation:	33 strains or lines available

Original:	J:166870 Watanabe Y, et al., Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development. Biochem J. 2010 Oct 25;432(1):47-55
All:	8 reference(s)