Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Vps26btm1Ktch
Name:	VPS26 retromer complex component B; targeted mutation 1, Kyu-Tae Chang
MGI ID:	MGI:4867701
Gene:	Vps26b  Location: Chr9:26919067-26941361 bp, - strand  Genetic Position: Chr9, 12.07 cM
Alliance:	Vps26btm1Ktch page

Germline Transmission:	Earliest citation of germline transmission: J:167062
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 5 and flanking intronic sequences were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:167062)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vps26b Mutation:	20 strains or lines available

Original:	J:167062 Kim E, et al., Implication of mouse Vps26b-Vps29-Vps35 retromer complex in sortilin trafficking. Biochem Biophys Res Commun. 2010 Dec 10;403(2):167-71
All:	2 reference(s)