Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Efna1tm1Jinc
Name:	ephrin A1; targeted mutation 1, Jin Chen
MGI ID:	MGI:4849544
Gene:	Efna1  Location: Chr3:89179037-89188258 bp, - strand  Genetic Position: Chr3, 39.04 cM
Alliance:	Efna1tm1Jinc page

Germline Transmission:	Earliest citation of germline transmission: J:166527
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis of P0 lung extracts. (J:166527)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Efna1 Mutation:	18 strains or lines available

Original:	J:166527 Frieden LA, et al., Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1. Dev Dyn. 2010 Dec;239(12):3226-34
All:	2 reference(s)