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Sh2d1b1tm1.1Cpt
Targeted Allele Detail
Summary
Symbol: Sh2d1b1tm1.1Cpt
Name: SH2 domain containing 1B1; targeted mutation 1.1, Cox Terhorst
MGI ID: MGI:4840390
Synonyms: EAT-2A-
Gene: Sh2d1b1  Location: Chr1:170104889-170114338 bp, + strand  Genetic Position: Chr1, 76.84 cM, cytoband H2
Alliance: Sh2d1b1tm1.1Cpt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166054
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 1 was replaced with a floxed neo cassette. Cre mediated recombination removed the neo cassette. (J:166054)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sh2d1b1 Mutation:  8 strains or lines available
References
Original:  J:166054 Wang N, et al., Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse. J Immunol. 2010 Nov 15;185(10):5683-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory