Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Spesp1tm1Osb
Name:	sperm equatorial segment protein 1; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI ID:	MGI:4838302
Synonyms:	Spesp1tm1Oka
Gene:	Spesp1  Location: Chr9:62178011-62189461 bp, - strand  Genetic Position: Chr9, 33.65 cM
Alliance:	Spesp1tm1Osb page

Germline Transmission:	Earliest citation of germline transmission: J:159611
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Part of exon 2 of the gene was replaced with neo resistant cassette. Western blot analysis confirmed the absence of proteins. This is a null allele. (J:159611)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Spesp1 Mutation:	22 strains or lines available

Original:	J:159611 Fujihara Y, et al., Sperm equatorial segment protein 1, SPESP1, is required for fully fertile sperm in mouse. J Cell Sci. 2010 May 1;123(Pt 9):1531-6
All:	3 reference(s)