Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wnt4tm1.2Boer
Name:	wingless-type MMTV integration site family, member 4; targeted mutation 1.2, Derek Boerboom
MGI ID:	MGI:4838181
Synonyms:	Wnt4-
Gene:	Wnt4  Location: Chr4:137004946-137026812 bp, + strand  Genetic Position: Chr4, 69.8 cM
Alliance:	Wnt4tm1.2Boer page

Germline Transmission:	Earliest citation of germline transmission: J:162337
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A genomic segment spanning exon 3 and exon 4 was removed by crossing Wnt4tm1.1Boer with cre deleter mice. This is a null allele. (J:162337)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt4 Mutation:	20 strains or lines available

Original:	J:162337 Boyer A, et al., WNT4 is required for normal ovarian follicle development and female fertility. FASEB J. 2010 Aug;24(8):3010-25
All:	2 reference(s)