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Ccn2tm1Mae
Targeted Allele Detail
Summary
Symbol: Ccn2tm1Mae
Name: cellular communication network factor 2; targeted mutation 1, Nobuyo Maeda
MGI ID: MGI:4838151
Gene: Ccn2  Location: Chr10:24471340-24474581 bp, + strand  Genetic Position: Chr10, 11.84 cM, cytoband A3-B1
Alliance: Ccn2tm1Mae page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165111
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin selection cassette replaced all of exons 3 through 5. (J:165111)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccn2 Mutation:  27 strains or lines available
References
Original:  J:165111 Doherty HE, et al., A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high. PLoS One. 2010;5(9):e12909
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory