Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Serpinb2tm2Dgi
Name:	serine (or cysteine) peptidase inhibitor, clade B, member 2; targeted mutation 2, David Ginsburg
MGI ID:	MGI:4837545
Synonyms:	PAI-2-, SerpinB215B11-
Gene:	Serpinb2  Location: Chr1:107439153-107453330 bp, + strand  Genetic Position: Chr1, 50.34 cM
Alliance:	Serpinb2tm2Dgi page

Germline Transmission:	Earliest citation of germline transmission: J:52283
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced exons 3-8. Western analysis of cultured monocytes did not detect immunoreactive protein in homozygous mutant mice. (J:52283)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serpinb2 Mutation:	32 strains or lines available

Original:	J:52283 Dougherty KM, et al., The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):686-91
All:	2 reference(s)