Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Eef2ktm1Agry
Name:	eukaryotic elongation factor-2 kinase; targeted mutation 1, Alexey G Ryazanov
MGI ID:	MGI:4819586
Gene:	Eef2k  Location: Chr7:120442080-120506441 bp, + strand  Genetic Position: Chr7, 64.95 cM, cytoband F3
Alliance:	Eef2ktm1Agry page

Germline Transmission:	Earliest citation of germline transmission: J:162129
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 7 and most of exon 8 were replaced with a neo cassette via homologous recombination. Western blot analysis confirmed the absence of protein expression in homozygous mice. (J:208406)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eef2k Mutation:	40 strains or lines available

Original:	J:162129 Khan AA, et al., Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway. Am J Pathol. 2010 Jul;177(1):481-92
All:	14 reference(s)