Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	B3gnt5tm1Nari
Name:	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5; targeted mutation 1, Hisashi Narimatsu
MGI ID:	MGI:4459891
Gene:	B3gnt5  Location: Chr16:19578958-19591503 bp, + strand  Genetic Position: Chr16, 12.23 cM, cytoband B1
Alliance:	B3gnt5tm1Nari page

Germline Transmission:	Earliest citation of germline transmission: J:161366
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The open reading frame containing exon 1 was replaced with a neomycin resistance gene by homologous recombination. RT-PCR confirmed the absence of the transcript in murine tissues. (J:161366)

Generation of the B3gnt5tm1Nari allele

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any B3gnt5 Mutation:	24 strains or lines available

Original:	J:161366 Togayachi A, et al., Lack of lacto/neolacto-glycolipids enhances the formation of glycolipid-enriched microdomains, facilitating B cell activation. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11900-5
All:	1 reference(s)