Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Timd4tm1Kuch
Name:	T cell immunoglobulin and mucin domain containing 4; targeted mutation 1, Vijay Kuchroo
MGI ID:	MGI:4459812
Synonyms:	TIM4-
Gene:	Timd4  Location: Chr11:46701627-46735159 bp, + strand  Genetic Position: Chr11, 28.09 cM
Alliance:	Timd4tm1Kuch page

Germline Transmission:	Earliest citation of germline transmission: J:160747
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exons 2-4 were replaced with a neo cassette by homologous recombination. (J:160747)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Timd4 Mutation:	27 strains or lines available

Original:	J:160747 Rodriguez-Manzanet R, et al., T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8706-11
All:	10 reference(s)