Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lrp1btm2Wtsi
Name:	low density lipoprotein-related protein 1B; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID:	MGI:4459800
Gene:	Lrp1b  Location: Chr2:40485258-42543636 bp, - strand  Genetic Position: Chr2, 24.51 cM, cytoband B
Alliance:	Lrp1btm2Wtsi page

Germline Transmission:	Earliest citation of germline transmission: J:160170
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Mice carry an internal duplication of exon 69 of Lrp1b, based on the Ensembl predicted gene structure predicted to cause frameshift mutations. (J:91707, J:160170)

Generation of the Lrp1btm2Wtsi allele

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lrp1b Mutation:	301 strains or lines available

Original:	J:160170 Dietrich MF, et al., Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo. PLoS One. 2010;5(4):e9960
All:	2 reference(s)