About   Help   FAQ
Gmnntm1.2Kio
Targeted Allele Detail
Summary
Symbol: Gmnntm1.2Kio
Name: geminin; targeted mutation 1.2, Dimitris Kioussis
MGI ID: MGI:4456373
Gene: Gmnn  Location: Chr13:24935828-24945906 bp, - strand  Genetic Position: Chr13, 10.64 cM
Alliance: Gmnntm1.2Kio page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159657
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed the neo cassette, exon 3 and exon 4. The absence of protein expression was confirmed by western blot analysis on thymus and spleen extracts. (J:159657)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gmnn Mutation:  26 strains or lines available
References
Original:  J:159657 Karamitros D, et al., Differential geminin requirement for proliferation of thymocytes and mature T cells. J Immunol. 2010 Mar 1;184(5):2432-41
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory