Kdm3atm1Jxu
Targeted Allele Detail
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| Symbol: |
Kdm3atm1Jxu |
| Name: |
lysine (K)-specific demethylase 3A; targeted mutation 1, Jianming Xu |
| MGI ID: |
MGI:4453574 |
| Synonyms: |
Jmjd1a- |
| Gene: |
Kdm3a Location: Chr6:71565954-71609963 bp, - strand Genetic Position: Chr6, 32.18 cM
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| Alliance: |
Kdm3atm1Jxu page
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Low testis weight and sperm count in Kdm3atm1Jxu/Kdm3atm1Jxu mice
Show the 2 phenotype image(s) involving this allele.
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| Germline Transmission: |
Earliest citation of germline transmission:
J:159956
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| Parent Cell Line: |
TC1/TC-1 (ES Cell)
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| Strain of Origin: |
129S6/SvEvTac
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 17 through 25 were replaced with a neo cassette. The absence of full length protein expression was confirmed by western blot analysis on testis extracts. Weak expression of a truncated peptide is detected by western blot analysis.
(J:159956)
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Generation of the Kdm3atm1Jxu allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Kdm3a Mutation: |
79 strains or lines available
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| Original: |
J:159956 Liu Z, et al., Jmjd1a demethylase-regulated histone modification is essential for cAMP-response element modulator-regulated gene expression and spermatogenesis. J Biol Chem. 2010 Jan 22;285(4):2758-70 |
| All: |
3 reference(s) |
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Analysis Tools
