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Clec5atm1Cua
Targeted Allele Detail
Summary
Symbol: Clec5atm1Cua
Name: C-type lectin domain family 5, member a; targeted mutation 1, Daniel J Cua
MGI ID: MGI:4441169
Synonyms: Mdl1-, MDL-1-
Gene: Clec5a  Location: Chr6:40551832-40562739 bp, - strand  Genetic Position: Chr6, 18.82 cM, cytoband B2
Alliance: Clec5atm1Cua page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158811
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 1 through 6 were replaced with a flanked neo cassette. (J:158811)
Generation of the Clec5atm1Cua allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clec5a Mutation:  18 strains or lines available
References
Original:  J:158811 Joyce-Shaikh B, et al., Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis. J Exp Med. 2010 Mar 15;207(3):579-89
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory