Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hdac1tm1.2Pmt
Name:	histone deacetylase 1; targeted mutation 1.2, Patrick Matthias
MGI ID:	MGI:4440558
Gene:	Hdac1  Location: Chr4:129409897-129436506 bp, - strand  Genetic Position: Chr4, 63.26 cM
Alliance:	Hdac1tm1.2Pmt page

Germline Transmission:	Earliest citation of germline transmission: J:157903
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 6 was floxed and a neo cassette with a 3' loxP site was inserted within intron 7. The selection cassette and exon 6 were removed by cre mediated recombination. (J:157903)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hdac1 Mutation:	36 strains or lines available

Original:	J:157903 Yamaguchi T, et al., Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev. 2010 Mar 1;24(5):455-69
All:	1 reference(s)