Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Snap23tm1.1Paro
Name:	synaptosomal-associated protein 23; targeted mutation 1.1, Paul A Roche
MGI ID:	MGI:4439388
Synonyms:	Snap23delta
Gene:	Snap23  Location: Chr2:120398152-120431736 bp, + strand  Genetic Position: Chr2, 60.37 cM, cytoband E5
Alliance:	Snap23tm1.1Paro page

Germline Transmission:	Earliest citation of germline transmission: J:158506
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was removed by cre mediated recombination. Reduced protein expression was confirmed by western blot analysis on extracts from heterozygous mice. (J:158506, J:171444)

Generation of the Snap23tm1Paro, Snap23tm1.1Paro, and Snap23tm1.2Paro alleles

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Snap23 Mutation:	31 strains or lines available

Original:	J:158506 Suh YH, et al., A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking. Nat Neurosci. 2010 Mar;13(3):338-43
All:	3 reference(s)