Slc20a1tm1.2Lbek
Targeted Allele Detail
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| Symbol: |
Slc20a1tm1.2Lbek |
| Name: |
solute carrier family 20, member 1; targeted mutation 1.2, Laurent Beck |
| MGI ID: |
MGI:4438614 |
| Synonyms: |
PiT1delta5 |
| Gene: |
Slc20a1 Location: Chr2:129040684-129053536 bp, + strand Genetic Position: Chr2, 62.79 cM
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| Alliance: |
Slc20a1tm1.2Lbek page
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Defective liver development and anemia in Slc20a1tm1.2Lbek/Slc20a1tm1.2Lbek embryos
Show the 7 phenotype image(s) involving this allele.
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| Germline Transmission: |
Earliest citation of germline transmission:
J:157997
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| Parent Cell Line: |
CK35 (ES Cell)
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| Strain of Origin: |
129S2/SvPas
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: An FRT flanked neo cassette was inserted in intron 5, and exon 5 was flanked 5' and 3' with loxP sites 532 bp upstream and 934 bp downstream. The selection cassette and exon 5 were removed by cre mediated recombination. Absence of transcript was confirmed by Northern blot analysis of E12.5 whole embryos.
(J:157997)
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Generation of the Slc20a1tm1Lbek, Slc20a1tm1.1Lbek and Slc20a1tm1.2Lbek alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Slc20a1 Mutation: |
36 strains or lines available
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| Original: |
J:157997 Beck L, et al., The phosphate transporter PiT1 (Slc20a1) revealed as a new essential gene for mouse liver development. PLoS One. 2010;5(2):e9148 |
| All: |
2 reference(s) |
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Analysis Tools
