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Arhgef5tm1.1Dwu
Targeted Allele Detail
Summary
Symbol: Arhgef5tm1.1Dwu
Name: Rho guanine nucleotide exchange factor 5; targeted mutation 1.1, Dianqing Wu
MGI ID: MGI:4437666
Synonyms: G5-
Gene: Arhgef5  Location: Chr6:43242578-43266254 bp, + strand  Genetic Position: Chr6, 21.15 cM
Alliance: Arhgef5tm1.1Dwu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157812
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre recombination removed exons 5 through 9. The absence of transcrpt expression was confirmed by RT-PCR on bone marrow cell extracts. (J:157812)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arhgef5 Mutation:  72 strains or lines available
References
Original:  J:157812 Wang Z, et al., Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5. J Biol Chem. 2009 Oct 16;284(42):28599-606
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory