Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Maged1tm1.1Urfm
Name:	MAGE family member D1; targeted mutation 1.1, Olivier De Backer
MGI ID:	MGI:4437118
Gene:	Maged1  Location: ChrX:93579080-93585631 bp, - strand  Genetic Position: ChrX, 41.56 cM
Alliance:	Maged1tm1.1Urfm page

Germline Transmission:	Earliest citation of germline transmission: J:157604
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 4-12 were floxed, and a floxed neo cassette was placed within intron 3 by homologous recombination. The neo cassette and floxed exons have been removed. Immunoblotting of brain lysates demonstrated that full-length protein was absent in homozygous animals. (J:157604)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Maged1 Mutation:	9 strains or lines available

Original:	J:157604 Bertrand MJ, et al., NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo. Cell Death Differ. 2008 Dec;15(12):1921-9
All:	6 reference(s)