Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Insl6tm1Imad
Name:	insulin-like 6; targeted mutation 1, Ibrahim M Adham
MGI ID:	MGI:4431170
Gene:	Insl6  Location: Chr19:29298754-29302718 bp, - strand  Genetic Position: Chr19, 23.82 cM, cytoband C3
Alliance:	Insl6tm1Imad page

Germline Transmission:	Earliest citation of germline transmission: J:157348
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR in testis extracts. (J:157348)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	16 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Insl6 Mutation:	9 strains or lines available

Original:	J:157348 Burnicka-Turek O, et al., Inactivation of insulin-like factor 6 disrupts the progression of spermatogenesis at late meiotic prophase. Endocrinology. 2009 Sep;150(9):4348-57
All:	2 reference(s)