Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Agr2tm1.2Lpkn
Name:	anterior gradient 2; targeted mutation 1.2, Steven M Lipkin
MGI ID:	MGI:4421689
Gene:	Agr2  Location: Chr12:36042924-36054080 bp, + strand  Genetic Position: Chr12, 16.18 cM
Alliance:	Agr2tm1.2Lpkn page

Germline Transmission:	Earliest citation of germline transmission: J:156704
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre mediated recombination removed exons 2 through 4. The absence of protein expression was confirmed by western blot analysis and immunohistochemistry. (J:156704)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Agr2 Mutation:	31 strains or lines available

Original:	J:156704 Zhao F, et al., Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice. Dev Biol. 2010 Feb 15;338(2):270-9
All:	2 reference(s)