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Kat6atm2.2Avo
Targeted Allele Detail
Summary
Symbol: Kat6atm2.2Avo
Name: K(lysine) acetyltransferase 6A; targeted mutation 2.2, Anne K Voss
MGI ID: MGI:4418468
Synonyms: Moz-
Gene: Kat6a  Location: Chr8:23349551-23433275 bp, + strand  Genetic Position: Chr8, 11.42 cM
Alliance: Kat6atm2.2Avo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155755
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 3 to 7 were flanked by loxP sites (after removal of an Frt-flanked "Pgk1-neomycinphotransferase" selection cassette). Exons 3 to 7 were deleted upon cre mediated recombination. (J:155755)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 64 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Kat6atm2.2Avo
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kat6a Mutation:  67 strains or lines available
References
Original:  J:155755 Voss AK, et al., Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity. Dev Cell. 2009 Nov;17(5):674-86
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory