Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Prkcitm1.1Kido Name: protein kinase C, iota; targeted mutation 1.1, Yoshiaki Kido MGI ID: MGI:4417855 Synonyms: aPKClambdadeleted Gene: Prkci  Location: Chr3:31049893-31106889 bp, + strand  Genetic Position: Chr3, 14.65 cM Alliance: Prkcitm1.1Kido page

Focal segmental glomerulosclerosis in Prkcitm1Kido/Prkcitm1.1Kido Tg(Nphs1-cre)33Mska/0 mice Show the 2 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:154910
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exon 5 has been deleted. (J:154910)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkci Mutation:	69 strains or lines available

Original:	J:154910 Sugiyama Y, et al., A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56
All:	3 reference(s)