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Chst1tm1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Chst1tm1(KOMP)Vlcg
Name: carbohydrate sulfotransferase 1; targeted mutation 1, Velocigene
MGI ID: MGI:4415360
Gene: Chst1  Location: Chr2:92430052-92445595 bp, + strand  Genetic Position: Chr2, 51.17 cM, cytoband D-E1
Alliance: Chst1tm1(KOMP)Vlcg page
IMPC: Chst1 gene page
Mutation
origin
Mutant Cell Lines:  10172A-D6, 10172B-A7, 10172B-D12
Germline Transmission:  Earliest citation of germline transmission: J:204813
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1285bp between positions 92443516-92444800 of Chromosome 2 (Build GRCm39). The lacZ and floxed neomycin resistance cassette replaced the coding sequence. (J:136110, J:204813)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Chst1 Mutation:  20 strains or lines available
Notes
Cell line 10172A-D6 was successfully used to make chimeric mice. Germline transmission was accomplished. J:204813
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory