Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fzr1tm1.2Stge
Name:	fizzy and cell division cycle 20 related 1; targeted mutation 1.2, Stephen Geley
MGI ID:	MGI:4410513
Gene:	Fzr1  Location: Chr10:81202713-81214204 bp, - strand  Genetic Position: Chr10, 39.72 cM
Alliance:	Fzr1tm1.2Stge page

Germline Transmission:	Earliest citation of germline transmission: J:154779
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre mediated recombination of Fzr1tm1.1Stge removed exons 2 through 8. (J:154779)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fzr1 Mutation:	43 strains or lines available

Original:	J:154779 Sigl R, et al., Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis. J Cell Sci. 2009 Nov 15;122(Pt 22):4208-17
All:	1 reference(s)