Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Wnt8atm1(KOMP)Vlcg
Name:	wingless-type MMTV integration site family, member 8A; targeted mutation 1, Velocigene
MGI ID:	MGI:4399164
Gene:	Wnt8a  Location: Chr18:34675380-34681114 bp, + strand  Genetic Position: Chr18, 18.69 cM, cytoband B3
Alliance:	Wnt8atm1(KOMP)Vlcg page
IMPC:	Wnt8a gene page

Mutant Cell Lines:	10481B-F10, 10481B-H3
Germline Transmission:	Earliest citation of germline transmission: J:194132
Parent Cell Line:	VGB6 (ES Cell)
Strain of Origin:	C57BL/6NTac
Project Collection:	KOMP-Regeneron

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1   Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 5486bp between positions 34675407-34680892 of Chromosome 18 (Build GRCm39). The entire coding sequence was replaced with a lacZ gene and floxed neo cassette. Whole mount RNA hybridization confirmed the absence of transcript expression in E8 embryos. (J:136110, J:194132)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

27 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Wnt8a Mutation:	15 strains or lines available

Original:	J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:	3 reference(s)