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Tcf3tm3.1Cmu
Targeted Allele Detail
Summary
Symbol: Tcf3tm3.1Cmu
Name: transcription factor 3; targeted mutation 3.1, Cornelis Murre
MGI ID: MGI:4366003
Synonyms: Tcfe2adeltaE12
Gene: Tcf3  Location: Chr10:80245348-80269481 bp, - strand  Genetic Position: Chr10, 39.72 cM
Alliance: Tcf3tm3.1Cmu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153423
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Germline, cre mediated recombination removed the E12 isoform-specific exon and the neo cassette. (J:153423)
Generation of Tcf3tm3Cmu, Tcf3tm3.1Cmu, Tcf3tm4Cmu, and Tcf3tm4.1Cmu alleles
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf3 Mutation:  39 strains or lines available
References
Original:  J:153423 Beck K, et al., Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci. J Exp Med. 2009 Sep 28;206(10):2271-84
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory