Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nfil3tm1.1Brad
Name:	nuclear factor, interleukin 3, regulated; targeted mutation 1.1, Hugh Brady
MGI ID:	MGI:4360908
Synonyms:	E4bp4-
Gene:	Nfil3  Location: Chr13:53121245-53135109 bp, - strand  Genetic Position: Chr13, 27.68 cM
Alliance:	Nfil3tm1.1Brad page

Germline Transmission:	Earliest citation of germline transmission: J:152774
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of the coding region and a floxed neo cassette was inserted downstream of the coding exon. Germ line, cre mediated recombination removes the neo cassette and coding exon. The absence of protein expression was confirmed by western blot analysis on heart extracts. (J:152774)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfil3 Mutation:	31 strains or lines available

Original:	J:152774 Gascoyne DM, et al., The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol. 2009 Oct;10(10):1118-24
All:	17 reference(s)