Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nipal3tm1Pbfd
Name:	NIPA-like domain containing 3; targeted mutation 1, Peter Burfeind
MGI ID:	MGI:4360699
Synonyms:	Npal3-
Gene:	Nipal3  Location: Chr4:135173454-135222283 bp, - strand  Genetic Position: Chr4, 67.64 cM, cytoband D3
Alliance:	Nipal3tm1Pbfd page

Germline Transmission:	Earliest citation of germline transmission: J:152829
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 3 through 8 were replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on brain extracts. (J:152829)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nipal3 Mutation:	43 strains or lines available

Original:	J:152829 Grzmil P, et al., Targeted disruption of the mouse Npal3 gene leads to deficits in behavior, increased IgE levels, and impaired lung function. Cytogenet Genome Res. 2009;125(3):186-200
All:	1 reference(s)