Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pak4tm2.2Amin
Name:	p21 (RAC1) activated kinase 4; targeted mutation 2.2, Audrey Minden
MGI ID:	MGI:4360338
Synonyms:	Pak4delta
Gene:	Pak4  Location: Chr7:28258244-28297609 bp, - strand  Genetic Position: Chr7, 16.84 cM
Alliance:	Pak4tm2.2Amin page

Germline Transmission:	Earliest citation of germline transmission: J:152821
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre mediated recombination removed exons 2 through 4 and the neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embyonic fibroblast extracts. (J:152821)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pak4 Mutation:	91 strains or lines available

Original:	J:152821 Tian Y, et al., Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation. Mech Dev. 2009 Aug-Sep;126(8-9):710-20
All:	2 reference(s)