Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pros1tm1.1Ansc
Name:	protein S (alpha); targeted mutation 1.1, Anne Angelillo-Scherrer
MGI ID:	MGI:4359168
Synonyms:	Pros-
Gene:	Pros1  Location: Chr16:62674670-62749709 bp, + strand  Genetic Position: Chr16, 36.43 cM
Alliance:	Pros1tm1.1Ansc page

Germline Transmission:	Earliest citation of germline transmission: J:152423
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre mediated recombination removes exons 3 through 7. The decreased protein expression was confirmed by western blot analysis on plasma from heterozygous mice. (J:152423)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pros1 Mutation:	44 strains or lines available

Original:	J:152423 Saller F, et al., Generation and phenotypic analysis of protein S-deficient mice. Blood. 2009 Sep 10;114(11):2307-14
All:	5 reference(s)